FEATURES

DESCRIPTION

Also known as ADAM9_HUMAN, ADAM9, KIAA0021, MCMP, MDC9, MLTNG. Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins., May act as alpha-secretase for amyloid precursor protein (APP). Interacts with SH3GL2 and SNX9 through its cytoplasmic tail (PubMed:10531379). Interacts with ITGA6.

Also known as ADAM9_HUMAN, ADAM9, KIAA0021, MCMP, MDC9, MLTNG. Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40 ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADAM9

Disintegrin and metalloproteinase domain-containing protein 9

ADAM9

Molecular Synopsis