FEATURES

FAMILY

DESCRIPTION

Also known as UBE4A_HUMAN, UBE4A, KIAA0126. Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

UBE4A

Ubiquitin conjugation factor E4 A

UBE4A

Molecular Synopsis