FEATURES

FAMILY

DESCRIPTION

Also known as FCN2_HUMAN, FCN2, FCNL. May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. Homotrimer (PubMed:17215869). Interacts with elastin. Interacts with MASP1 and MASP2. Interacts with CR1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

FCN2

Ficolin-2

FCN2

Molecular Synopsis