FEATURES

FAMILY

DESCRIPTION

Also known as UPP1_HUMAN, UPP1, UP. Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7488099). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

UPP1

Uridine phosphorylase 1

UPP1

Molecular Synopsis