FEATURES

FAMILY

DESCRIPTION

Also known as KCNT1_HUMAN, KCNT1, KIAA1422. Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity). Interacts (via C-terminus) with FMR1; this interaction alters gating properties of KCNT1 (PubMed:20512134). Interacts with CRBN via its cytoplasmic C-terminus (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KCNT1

Potassium channel subfamily T member 1

KCNT1

Molecular Synopsis