FEATURES

FAMILY

DESCRIPTION

Also known as DODEC_THET8, TTHA1431. May function as storage protein that sequesters various flavins and other cofactors, thereby protecting the cell against undesirable reactions mediated by the free cofactors. Binds and sequesters FMN, FAD, lumiflavin and lumichrome, and can also bind coenzyme A. Homododecamer; four homotrimers assemble to form a dodecameric hollow sphere with an outer diameter of about 60 Angstroms. Flavin dimers are bound between subunits with a stoichiometry of 6 flavin dimers per dodecamer. Besides, trimeric coenzyme A molecules can be bound between subunits. A dodecamer can bind simultaneously 12 flavin and 12 coenzyme A molecules.

EXTERNAL LINKS

uniprot
enzyme classification

TTHA1431

Dodecin

TTHA1431

Molecular Synopsis