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FEATURES

FAMILY

STE Ser/Thr protein kinase family

DESCRIPTION

Also known as M3K21_HUMAN, MAP3K21, KIAA1804, MLK4. Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. Homodimer (By similarity). Interacts with TLR4.

Also known as M3K21_HUMAN, MAP3K21, KIAA1804, MLK4. Negative regulator of TLR4 signaling. Does not activate JNK1/MAPK8 pathway, p38/MAPK14, nor ERK2/MAPK1 pathways. Homodimer (By similarity). Int ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MAP3K21

Mitogen-activated protein kinase kinase kinase 21

Molecular Synopsis

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