FEATURES

FAMILY

DESCRIPTION

Also known as PTK7_DROME, otk. Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons. Interacts with plexA; component of a receptor complex that mediates the repulsive signaling in response to Semaphorin ligands.

EXTERNAL LINKS

uniprot
enzyme classification

otk

Tyrosine-protein kinase-like otk

otk

Molecular Synopsis