FEATURES

FAMILY

DESCRIPTION

Also known as MAST2_HUMAN, MAST2, KIAA0807, MAST205. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). Interacts with CDHR2.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MAST2

Microtubule-associated serine/threonine-protein kinase 2

MAST2

Molecular Synopsis