FEATURES

FAMILY

DESCRIPTION

Also known as DUSTY_HUMAN, DSTYK, KIAA0472, RIP5, RIPK5, SGK496. Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, PubMed:28157540). Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PubMed:15178406). In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PubMed:28157540).

Also known as DUSTY_HUMAN, DSTYK, KIAA0472, RIP5, RIPK5, SGK496. Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DSTYK

Dual serine/threonine and tyrosine protein kinase

DSTYK

Molecular Synopsis