No data available

FEATURES

FAMILY

Ser/Thr protein kinase family

DESCRIPTION

Also known as ERN2_HUMAN, ERN2, IRE2. Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

Also known as ERN2_HUMAN, ERN2, IRE2. Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein res ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ERN2

Serine/threonine-protein kinase/endoribonuclease IRE2

Molecular Synopsis

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