FEATURES

FAMILY

short-chain dehydrogenases/reductases (SDR) family

DESCRIPTION

Also known as DCXR_HUMAN, DCXR, SDR20C1. Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. Homotetramer.

Also known as DCXR_HUMAN, DCXR, SDR20C1. Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cyc ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DCXR

L-xylulose reductase

DCXR

Molecular Synopsis