FEATURES

FAMILY

short-chain dehydrogenases/reductases (SDR) family

DESCRIPTION

Also known as RDH11_HUMAN, RDH11, ARSDR1, PSDR1, SDR7C1. Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a lesser extent on 13-cis-retinol (PubMed:12226107, PubMed:12036956, PubMed:29410696). Exhibits a low reductive activity towards unsaturated medium-chain aldehydes such as cis -6-nonenal and no activity toward nonanal or 4-hydroxy-nonenal (PubMed:15865448). Has no dehydrogenase activity towards steroid (PubMed:12226107, PubMed:12036956). Interacts with SELENOF.

Also known as RDH11_HUMAN, RDH11, ARSDR1, PSDR1, SDR7C1. Retinol dehydrogenase with a clear preference for NADP. Displays high activity towards 9-cis, 11-cis and all-trans-retinol, and to a less ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RDH11

Retinol dehydrogenase 11

RDH11

Molecular Synopsis