FEATURES

DESCRIPTION

Also known as CIP2A_HUMAN, CIP2A, KIAA1524. Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation. Homodimer (PubMed:28174209). Interacts with MYC (PubMed:17632056). Interacts with PPP2R5C; this interaction stabilizes CIP2A (PubMed:28174209). Interacts with PPP2R1A; this interaction stabilizes CIP2A (PubMed:28174209).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CIP2A

Protein CIP2A

CIP2A

Molecular Synopsis