FEATURES

FAMILY

DESCRIPTION

Also known as KAT6B_HUMAN, KAT6B, KIAA0383, MORF, MOZ2, MYST4. Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts with RUNX1 and RUNX2.

Also known as KAT6B_HUMAN, KAT6B, KIAA0383, MORF, MOZ2, MYST4. Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-depend ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KAT6B

Histone acetyltransferase KAT6B

KAT6B

Molecular Synopsis