FEATURES

FAMILY

DESCRIPTION

Also known as PTPRU_HUMAN, PTPRU, FMI, PCP2, PTPRO. Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis. Forms homooligomeric complexes which mediate cell homotypic adhesion (Probable). Interacts (via the cytoplasmic juxtamembrane domain) with CTNNB1; may mediate interaction with the cadherin/catenin adhesion complex. Interacts with KIT. May interact with AP3B1.

Also known as PTPRU_HUMAN, PTPRU, FMI, PCP2, PTPRO. Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PTPRU

Receptor-type tyrosine-protein phosphatase U

PTPRU

Molecular Synopsis