FEATURES

FAMILY

DESCRIPTION

Also known as M3K3_HUMAN, MAP3K3, MAPKKK3, MEKK3. Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. Binds both upstream activators and downstream substrates in multimolecular complexes. Part of a complex with MAP2K3, RAC1 and CCM2. Interacts with MAP2K5 and SPAG9.

Also known as M3K3_HUMAN, MAP3K3, MAPKKK3, MEKK3. Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators. Binds ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MAP3K3

Mitogen-activated protein kinase kinase kinase 3

MAP3K3

Molecular Synopsis