FEATURES

FAMILY

SLC29A/ENT transporter (TC 2.A.57) family

DESCRIPTION

Also known as S29A1_HUMAN, SLC29A1, ENT1. Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs). Identified in a complex with STOM.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC29A1

Equilibrative nucleoside transporter 1

SLC29A1

Molecular Synopsis