FEATURES

FAMILY

DESCRIPTION

Also known as KCNS3_HUMAN, KCNS3. Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1 (PubMed:10484328). Heterotetrameric channel activity formed with KCNB1 show increased current amplitude with the threshold for action potential activation shifted towards more negative values in hypoxic-treated pulmonary artery smooth muscle cells (By similarity). Heterotetramer with KCNB1 (PubMed:10484328). Does not form homomultimers (PubMed:10484328).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KCNS3

Potassium voltage-gated channel subfamily S member 3

KCNS3

Molecular Synopsis