FEATURES

FAMILY

short-chain dehydrogenases/reductases (SDR) family

DESCRIPTION

Also known as PECR_HUMAN, PECR, SDR29C1. Participates in chain elongation of fatty acids. Catalyzes the reduction of trans-2-enoyl-CoAs of varying chain lengths from 6:1 to 16:1, having maximum activity with 10:1 CoA. Has no 2, 4-dienoyl-CoA reductase activity. Interacts with PEX5, probably required to target it into peroxisomes.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PECR

Peroxisomal trans-2-enoyl-CoA reductase

PECR

Molecular Synopsis