FEATURES

FAMILY

DESCRIPTION

Also known as UCK2_HUMAN, UCK2, UMPK. Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

UCK2

Uridine-cytidine kinase 2

UCK2

Molecular Synopsis