FEATURES

FAMILY

DESCRIPTION

Also known as MO2R1_MOUSE, Cd200r1, Mox2r, Ox2r. Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. CD200 and CD200R1 interact via their respective N-terminal Ig-like domains.

EXTERNAL LINKS

uniprot
enzyme classification

Cd200r1

Cell surface glycoprotein CD200 receptor 1

Mutations

Mutation(s) distribution

Mutations table

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