FEATURES

FAMILY

DESCRIPTION

Also known as KLC2_HUMAN, KLC2. Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosomes movement toward microtubule plus ends (PubMed:22172677). Oligomeric complex composed of two heavy chains and two light chains (Probable). Interacts (via TPR repeats) with PLEKHM2 (Probable).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KLC2

Kinesin light chain 2

KLC2

Molecular Synopsis