FEATURES

FAMILY

DESCRIPTION

Also known as WNT8A_HUMAN, WNT8A, WNT8D. Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in embryonic patterning. Forms a soluble 1:1 complex with AFM; this prevents oligomerization and is required for prolonged biological activity (PubMed:26902720). The complex with AFM may represent the physiological form in body fluids (PubMed:26902720).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

WNT8A

Protein Wnt-8a

WNT8A

Molecular Synopsis