FEATURES

FAMILY

DESCRIPTION

Also known as S1PR5_HUMAN, S1PR5, EDG8. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

S1PR5

Sphingosine 1-phosphate receptor 5

S1PR5

Molecular Synopsis