FEATURES

FAMILY

DESCRIPTION

Also known as VEZA_HUMAN, VEZT. Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. Required for morphogenesis of the preimplantation embryo, and for the implantation process., (Microbial infection) In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site. Interacts with USH2A (via the cytoplasmic region); the interaction associates VEZT with the USH2 complex at the stereocilia base (By similarity). Interacts with myosin MYO7A and the cadherin-catenins complex (PubMed:11080149).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

VEZT

Vezatin

VEZT

Molecular Synopsis