FEATURES

FAMILY

DESCRIPTION

Also known as EMAL4_HUMAN, EML4, C2orf2, EMAPL4. Essential for the formation and stability of microtubules (MTs) (PubMed:16890222, PubMed:31409757). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (PubMed:25789526). Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (PubMed:25789526). Interacts (via WD repeats) with NUDC (PubMed:25789526). Interacts with alpha- and beta-tubulin during mitosis (PubMed:31409757).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EML4

Echinoderm microtubule-associated protein-like 4

EML4

Molecular Synopsis