FEATURES

FAMILY

class-I pyridine nucleotide-disulfide oxidoreductase family

DESCRIPTION

Also known as TRXR2_HUMAN, TXNRD2, KIAA1652, TRXR2. Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690). Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TXNRD2

Thioredoxin reductase 2, mitochondrial

TXNRD2

Molecular Synopsis