FEATURES

DESCRIPTION

Also known as MBIP1_HUMAN, MBIP. Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Component of the ADA2A-containing complex (ATAC), composed of KAT14, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, KAT14 and WDR5.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MBIP

MAP3K12-binding inhibitory protein 1

MBIP

Molecular Synopsis