FEATURES

FAMILY

DESCRIPTION

Also known as DHCR7_HUMAN, DHCR7, D7SR. 7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5, 7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5, 7, 24-trien-3beta-ol, two intermediates in that pathway. Interacts with DHCR24; this interaction regulates DHCR7 activity.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DHCR7

7-dehydrocholesterol reductase

DHCR7

Molecular Synopsis