FEATURES

FAMILY

DESCRIPTION

Also known as STX8_HUMAN, STX8. Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER. Forms a SNARE complex with STX7, VTI1B and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, VAMP8 and VTI1B. Interacts with VAMP8 (By similarity). Interacts with HECTD3 (By similarity). Interacts with TPC1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

STX8

Syntaxin-8

STX8

Molecular Synopsis