FEATURES

FAMILY

DESCRIPTION

Also known as A3LT2_HUMAN, A3GALT2, A3GALT2P, IGBS3S. Synthesizes the galactose-alpha(1, 3)-galactose group on the glycosphingolipid isoglobotrihexosylceramide or isogloboside 3 (iGb3) by catalyzing the transfer of galactose from UDP-Galactose to its acceptor molecule Gal-beta-1, 4-Glc-ceramide. Can also catalyze the addition of galactose to iGb3 itself to form polygalactose structures.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

A3GALT2

Alpha-1, 3-galactosyltransferase 2

A3GALT2

Molecular Synopsis